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Natural American Spirit is a brand of Santa Fe Natural Tobacco Company, a subsidiary of Reynolds American Inc.
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In contrast, we estimate that cigarettes acquired in Mexico represented a large percentage of total cigarette consumption in four Southwestern states: New Mexico (18.3 percent), California (15.5 percent), Arizona (13.3 percent) and Texas (8.7 percent)
The heating of e-cig fluid generates an aerosol that contains humectants (vegetable glycerin, propyl glycol) and their toxic byproducts when heated (reactive aldehydes, volatile organic compounds), flavorings, heavy metals, and nicotine
Thirdly, although our analysis identified population-level associations, observational design inherently limits causal inference, and linear trend assumptions (such as EAPC) may oversimplify complex temporal dynamics affected by sudden policy shifts
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