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[4] As nicotine activates the same reward pathway as other drugs, it can often make other substances feel more rewarding, leading to polysubstance use

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To determine the effectiveness of such laws, Nesson and a team including Chad Cotti of Michigan State University and Phillip DeCicca of Ball State University used data from the Population Assessment of Tobacco Use and Health (PATH), an ongoing study that has been collecting information from thousands of participants since 2013

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