long term inhalation of cigarette smoke often leads to Smoking Effects on Lungs What to know about the

Chemistry, composition, and sources of air pollution Polluted air is a constantly changing combination of particle and gaseous phase components that vary in location and time (3, 74, 75)

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Notably, a recent study examined type I primary alveolar epithelial cells and showed that exposure to ozone increases cellular ROS levels, which activate PINK1-Parkin-mediated mitophagy and further promote NLRP3 inflammasome-mediated pyroptosis [48]