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Acknowledgments Many thanks to Dr Nicole Vellios for her valuable feedback on an earlier draft and for her general guidance on formatting and the Tobacco Control submission process

Although more work is needed to understand how the gut microbiota breaks down nicotine, the study reveals that the accumulation of this chemical in the gut is a risk factor for NAFLD progression in people who smoke.

Senegal, Niger, Turkmenistan, Uganda, and Oman make up the bottom 10, as the countries that smoke the least

With options that deliver authentic flavors and smooth satisfaction, the transition from traditional smokers to modern vapes has never been easier or more exciting

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