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If you want to know how many packs (PL) or cigarettes (CL) you have already smoked in your life, use the formula: PL = (Cigarettes per day/Pack_size) 365.24 Years CL = Cigarettes per day 365.24 Years Example of pack year calculation One pack year is equivalent to smoking 20 cigarettes a day for one year (1 pack 1 year)

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PINK1/Parkin-mediated mitophagy is initiated by the accumulation of PINK1 at the outer membrane of mitochondria, leading to the recruitment of cytoplasmic Parkin to those mitochondria