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The presence of carbonyl compounds, such as formaldehyde, in e-cigarette aerosols results from the heated degradation of e-liquid components (e.g., propylene glycol and glycerin) and depends on device features (e.g., closed vs open systems) and device settings (e.g., heating temperature and voltage) and result in higher HPHC levels in e-cigarette aerosols from some devices [11, 56,57,58,59]

(Women, too, were profiled by some cigarette brands)

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The nicotine effect on the adrenal gland can lead to an elevation in testosterone, but also increases levels of adrenaline (causing rises in blood pressure), and cortisol (a stress hormone)