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LVE W is the portion of the TTI curve attributed to earlier reflection of the pulse pressure wave (a shortening of t p in Figure 1) which increases central aortic pressure during systole and can be interpreted as the excess amount of energy expended by the left ventricle without a commensurate increase in flow

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He also defended his patent in court, showing his belief in the future of this invention

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While these devices continue to be promoted as safer alternatives to combustible cigarettes, their impact on on vascular function, lung function and subjective experiences remains almost entirely unknown