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It has also been shown that cbNPs accumulate in antigen-presenting dendritic cells derived from emphysematous lung tissue of smokers [73] and that cigarette smoke triggers the NLRP3 inflammasome [63], which is again consistent with the observation that IL-1 levels are elevated in smokers lungs [19]

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In traditional acupuncture, acupuncture needles or a low level laser is used on the auricular points of the ears, and also on the nose, hands, wrist and forearm