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The thousands of chemicals in tobacco smoke cause damage through several key mechanisms, each contributing to an increased risk of cognitive decline

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"When you smoke, your body absorbs a number of chemicals, including nicotine, and it has to work hard to clear those chemicals out." While nicotine itself doesnt stay in your body for long, the chemicals it breaks down to last in your system for days or weeks

American Journal of Epidemiology 2002 Aug 1;156(3):268-73

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