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Because e-cigarettes do not burn tobacco, the reduction of harmful substances depends on the chemical composition of the e-liquid, as well as the characteristics of the device 4,5,15,47,48,49

Specifically, we are proposing to consider a submission valid and ( scorable (including, potentially, a score of zero) for the applicable MIPS performance category only if the data submission includes: numerator and denominator data for at least one MIPS quality measure in the quality performance category

But the digestive system keeps a longer record

One study found that these products might deliver different levels of nicotine during each use and there were significant differences between labeled and true levels of nicotine in juices

Primary inclusion criteria included scoring 5 or higher on the FTCD, willingness to abstain from smoking for four hours prior to each laboratory visit and being between 18 and 65 years of age