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For comparison, snus (weight: one gram per pouch, 8 mg nicotine/pouch) was tested in the first part

Unlike conventional smoking, these products heat tobacco instead of burning it, reducing the release of harmful chemicals

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Over that same period, about 157,000 of them died

Study author Ludmil Alexandrov said in a statement that before now, we had a large body of epidemiological evidence linking smoking with cancer, but now we can actually observe and quantify the molecular changes in the DNA due to cigarette smoking. Co-author Sir Mike Stratton added that looking in the DNA of cancers can provide provocative new clues to how cancers develop and thus, potentially, how they can be prevented.