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It was discovered that prenatal Exposure to cigarette smoke hinders the development of the orbitofrontal cortex, increasing the chance using drugs in teenagers

Modulating KMO gene expression could be a useful tactic for the treatment of tobacco dependence ( KMO is reduced in schizophrenia and in bipolar patients with a history of psychosis ( KMO SNPs were found frequently in schizophrenia patients compared with healthy controls ( Integrated bioinformatics approaches were used to show the differentially expressed genes (DEGs) in smokers and non-smokers

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