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A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes

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However, the high nicotine delivery of the product and the scores on this study suggest that JUUL is probably as addictive as cigarettes. According to the researchers, the high addiction potential of these e-cigarettes is an important reason why non-smokers should not try them but they may provide a way for smokers to switch to a less harmful form of nicotine consumption

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