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"If they were used to stop people smoking or vaping, they could have a positive public health effect - but it would only be positive if they were used by those wanting to quit, not those who are trying nicotine for the first time." While they may carry fewer health risks than cigarettes and vapes, there are cardiovascular risks for people using pouches with high quantities of nicotine - and there is growing concern over the damage nicotine pouches do to gums
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Activation of lung fibroblasts and extracellular matrix production, such as MMPs and tissue inhibitors of metalloproteinases (TIMPs), is also a result of CS exposure [258,259]
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