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and (3) the pro-apoptotic effectors of apoptosis, BAX, BAK (and BOK), with the first two inhibited by the pro-survival BCL-2 proteins in healthy cells [6]
Do not cause birth defects if pregnancy occurs
(2017)) includes structured monitoring of: (i) nicotine withdrawal symptoms using the 8-item Minnesota Nicotine Withdrawal Scale (Hughes, 2007b) to examine: anger/irritability/frustration, anxiety or nervousness, depression/sad mood, desire/craving to smoke, difficulty concentrating, increased appetite/hunger/weight gain, insomnia/sleep problems/awakening at night, and restlessness/impatience, and (ii) the most common adverse side effects of psychiatric medications, i.e., dry mouth, increased thirst, drowsiness, tiredness, fatigue, increased sleep, blurred vision, dizziness, headache, increased sweating, increased salivation, and nausea (Lapshin, Skinner and Finkelstein, 2006)
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