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While vaping has taken center stage in recent years, traditional cigarettes remain a concern for teens

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The two studies that evaluated the effect of smoking on mirtazapines pharmacokinetics show significantly lower mirtazapine and their main active metabolites (S-mirtazapine and R-N-desmethylmirtazapine) serum levels in smokers than in nonsmokers

But what is so fascinating about this is that its an aesthetic cultural trend that doesnt seem to be impacting the actual smoking rates, which are still going down year over year