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"There is virtually no systematic research showing that increasing the smoking age prevents a teen from picking up the habit." This seemingly common-sense approach, however, doesn't work

These may operate sequentially: dependence erodes self-regulatory capacity for physical activity 16 , which in turn removes a key buffer against depression, allowing depressive affect to accumulate through neuro-immunological pathways that promote disease 17,18

polycombusted use RR = 2.59, CI [1.60, 4.21])

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