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And as part of that I think its important to develop manufacturing standards so that e-cigarettes are more consistent, less variable, and easier to study, which would move research and public health initiatives further faster. Media Contact: Kendall Daniels, Communication Specialist, UNC Health | UNC School of Medicine

While traditional tobacco control measures have achieved commendable declines in smoking rates, recent policies including increased tobacco taxation and a ban on consumer vapes have inadvertently fuelled a burgeoning nicotine black market

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Use may also be associated with pancreatitis and peptic ulcers

The results of MR analysis were influenced by potential SNPs, as could be seen by the leave-one-out plot, so conclusions needed to be drawn with caution (Supplementary Figure S2)