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At a 20 pack year threshold, diagnosis of ACP was observed earlier and patients had more frequent calcifications
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Other symptoms and signs of acid reflux include: Bad breath Bloating Burping or passing gas, especially after meals Chest pain Chronic cough Difficulty swallowing Gum bleeding or irritation Nausea Pain when swallowing Untreated GERD sometimes leads to more serious complications, like loss of appetite and persistent vomiting
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Our results confirm the early study of Gable 6 who found that the margin of safety (defined as therapeutic index) varied dramatically between substances
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