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There is a reversal agent called naloxone* that is a critical part of treatment as it manages the symptoms of central nervous system depression, seizures, and respiratory depression, which can quickly develop into respiratory arrest and death

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Effective management of opioid withdrawal symptoms: A gateway to opioid dependence management

This produces an inhalable vapor that delivers nicotine and minty flavor

Some findings raise potential concerns about sleep disturbances, although evidence remains minimal