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excess, surplus

Total nicotine (mg) = E-liquid volume (mL) Nicotine strength (mg/mL) Cigarette equivalent = Total nicotine 12 mg per cigarette Pack equivalent = Cigarette equivalent 20 Example: A 50,000-puff disposable with 22 mL of 50 mg/mL (5%) e-liquid contains 22 50 = 1,100 mg total nicotine about 92 cigarettes (1,100 12) or 4.6 packs

32 However, at no point in this voluminous material is the FDA explicit about how it will process the required information or make its APPH determination

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However, a rough estimate often used is that one disposable vape or E-Cigarette refill can be roughly equivalent to about 20 to 40 cigarettes, depending on the nicotine content of the e-liquid and the user's vaping habits