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However, it is important to keep in mind key limitations, namely that the evidence available is primarily specific to the US population and may not generalize to other populations, and that the small sample size of PWNS who use ECs introduces uncertainty into these results and may fail to detect some significant associations

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Quit aids including short-acting Nicotine Replacement Therapy (nicotine gum, lozenge, mouth spray, or inhaler) and the prescription medication varenicline may make it easier to reduce your nicotine consumption