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The statutory formula beginning in 2021/22 allocates: one percent of the MSA receipt to National Cancer Institute awardees to be distributed based on federal awards 12.6 percent of the MSA receipt for broad-based research 70 percent to National Institute of Health awardees to be distributed based on federal awards 30 percent to be allocated as follows: $1 million is to be used for spinal cord injury research Of the remainder, 75 percent is to be used for pediatric cancer research and 25 percent for capital and equipment grants to biotechnology research entities Prior to 2021/22, the 30 percent portion, now specifically allocated, was competitively awarded based on the research priorities determined by the Secretary of Health and the Health Research Advisory Committee

This approach has been recently criticized by Hughes and Shiffman [53], who noted three problems: "First, almost all disorders are syndromes that, by definition, are composed of multiple signs and symptoms

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