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Given the skewed distribution of biomarkers, we used Spearmans rank correlation coefficient (rsp) to assess the association between biomarkers

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Regarding the first thing, I am aware that I am not smoking the same mixture that the man from the 70s who bought this tobacco smoked, because the passage of time has made it change and as will be explained at the end of this review, fifty years ago people used not to store tobaccos, but used to smoke them immediately after buying them