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Determining this association epidemiologically will create another motivation to combat nicotine dependence

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Evidence was mounting that smokers had poorer health outcomes than their non-smoking counterparts

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In a randomized crossover trial comparing healthy subjects who smoked tobacco (maximum of 10 cigarettes per month), the acute use of nicotine-containing e-cigarettes significantly increased levels of circulating endothelial progenitor cells (flow cytometry) to the same magnitude as after smoking a traditional cigarette (41)