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Coronary Heart Disease and Stroke DeathsUnited States, 2006

Clinical and experimental data have also shown that cigarette smoking is a main risk factor for the induction of inflammatory diseases, such as ulcers and Crohns disease

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6 Other factors that may support a diagnosis but are not pathognomonic include family history, which is present in 40% of patients, 7 and recurrent inflammatory lesions elsewhere including pilonidal sinuses, acne conglobata (severe nodulocystic acne), and dissecting cellulitis (pustules and nodules on the scalp)

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