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However, the PHEs report, entitled Evidence Review of E-Cigarettes and Heated Tobacco Products 2018, also warned that heated tobacco products are likely to be considerably more harmful than e-cigarettes

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Indeed, a significant decrease in Smad2 phosphorylation was only observed when CSE was combined with the highest dose of UVA (20 kJ/m 2 UVA) and not with the other combinations, while a decrease in procollagen I levels was also induced when CSE was combined with 5 and 10 kJ/m 2 UVA (Fig