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However, no previous review has proposed a standardized framework to classify contamination levels based on abundance, determined the proportion of cigarette butts among global litter, or examined how protection status or management restrictions influence cigarette butt contamination across protected areas, despite their relevance to conservation policy [12, 31, 32]

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As these chemicals are filtered by the kidneys and excreted through urine, they can interact with cells, potentially leading to DNA damage and cancerous growth