Med Princ Pract 25(Suppl 2):4159 Crowley-Weber CL, Dvorakova K, Crowley C, Bernstein H, Bernstein C, Garewal H, Payne CM (2003) Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis
This rule ensures that any potential issues can be addressed quickly and safely
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the smoke comes cooler, which is a nice change
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