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Signs and symptoms of nicotine poisoning include: A fast or slow heartbeat Belly cramps Breathing problems Headache Vomiting If you think you have nicotine poisoning, call emergency services (911) or Poison Control (800-222-1222) right away

In clinical trials, the issue may arise as to how to identify individuals who are unwilling or unable to quit, that is, the criteria to be used to make this determination as well as how and when to intervene with smokers, who use PREPs, to help them eventually achieve abstinence

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For SATURN 2007-2010