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Under the ISO regimen, the regular IQOS tobacco stick on average yielded 0.30 mg of nicotine,21 while under the HCI regimen2226 29 30 nicotine levels in mainstream aerosol were 1.101.41 mg for IQOS, 0.46 mg for glo,29 and 2.56 mg per 100 puffs or 0.36 mg per single use/14 puffs for iFuse30 (table 3)

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