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Some of the differences between severe allergic reactions and common allergic reactions include: Speed of onset Anaphylaxis can develop rapidly, within minutes to an hour after exposure to the allergen
Polansky et al., Chromium Supplementation of Human Subjects: Effects on Glucose, Insulin and Lipid Parameters, Metabolism, 1983;32:89499
So it hardly qualifies as a drug of abuse.
When absorbed through the skin via a patchor through the mouth and stomach when chewing nicotine gumnicotine is absorbed more slowly and therefore takes longer to reach the brain
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