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Because of the high propensity of Blacks to favor menthol cigarettes, the FDA has framed its case as a pivotal moment for health equity. The FDAs Tobacco Product Scientific Advisory Committee has concluded that in addition to reducing the harshness of smoking, menthol in cigarettes is associated with increased initiation, higher dependence and lower quit success. Members of the Center for Tobacco Studies at Rutgers University have authored or co-authored 26 research studies cited by the FDA in its proposed product standard for menthol cigarettes

Therefore, it is plausible that the increased susceptibility to disease progression and the subsequent fatal outcome in this population is related to poor angiotensin 1-7 (Ang-1-7) generation, the main peptide generated by ACE2, and probably to their inaccessibility to its anti-inflammatory effects

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