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Sarah Skolnick found that reducing nicotine in cigarettes to minimally addictive levels could prevent millions of premature deaths, significantly reduce smoking disparities among people with major depression, and generate substantial economic benefits through increased productivity

Ethical approval for this study was obtained from the Ethical Review Board of Baqai Dental College (Reference Number: BDC/ERB/2023/050)

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The dextrorotatory form, (+)-nicotine is physiologically less active than ()-nicotine

Each data source has strengths and limitations associated with the methodology used