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Studies suggest that on average, a typical vaper consumes 2-3 milliliters of e-liquid daily, equivalent to about one pack of cigarettes in terms of nicotine intake

By contrast, a New Zealand case-control study found an increased risk of lung cancer associated with heavy cannabis use, with an exposure-response trend (84)

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when smoking duration was substituted for pack years as a dichotomous measure that may approximate childhood smoking, the association between childhood smoking and COPD risk was no longer confounded

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