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It can also lower the seizure threshold, which is one reason clinicians screen for seizure history and certain eating disorders before prescribing it

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But even more damaging was Talman's heavy smoking throughout adulthood, leading to his contracting lung cancer

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Farmers lost their farms or went heavily into debt just to put in their crop for the coming year. In other words, when Dukes buyers stopped paying tobacco farmers the higher rates they were used to getting and instead began offering them 1, 2, or 3 cents per pound, tobacco farmers in Bracken County and elsewhere couldnt make enough money to feed their families and stay solvent (it cost roughly 6 or 7 cents per pound to raise tobacco back then, per Gregory)