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Tobacco chewing is associated with serious health problems Tobacco contains many different chemicals called as carcinogens which can cause cancer

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However, their intensity typically decreases significantly with sustained sobriety and proper support

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A cumulative asbestos exposure of 25 fiber-yrs is also the level accepted as being associated with an approximate doubling of lung cancer risk relative to a nonexposed person i.e., additive increase in rate (risk) ratio (RR) from 1 to 2 for mixed fiber type exposures according to De Vuyst [104]