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Natl Libr Med 203:16773 Schaller JP, Keller D, Paget L, Pratte P, Kaelin E, McHugh D, Cudazzo G, Smart D et al (2016a) Evaluation of the Tobacco Heating System 2.2

Its kind of depressing

While the world has educated itself about its ills, there are a few that still cling to their cigarettes for one particular reason: they say it makes them poop

The findings suggest nicotine exposure, whether from cigarettes or vaping devices, may influence blood pressure partly through its effect on cholesterol and blood vessel function

Guidance from the Centers for Disease Control and Prevention (CDC) emphasizes the risks of nicotine addiction and its impact on brain development, motivating some users to adopt zero-nicotine alternatives