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The Complex Nature of Tooth Discoloration Tooth discoloration develops through various mechanisms affecting both the enamel and underlying dentin

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Hristova VA, Beasley SA, Rylett RJ, Shaw GS

In the group of case-control studies, one study received nine yes answers [36], three studies received eight yes answers [35, 41, 54], one seven positive answers [55] and thus they having a low risk of bias