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However, most smokers adjust quickly as they become familiar with the draw and nicotine delivery

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Tangs team had shown in a February 2018 PNAS article that e-cigarette smoke induces DNA damage in the mouse lung and bladder, and that nitrosation in cultured human lung and bladder cells converts nicotine into derivatives that increase DNA code changes, or mutations, with the potential to transform normal cells into cancer cells

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it requires awareness and discipline