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These were excluded in order to maximize comparability among included studies

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Tobacco smoke contains various carcinogens, including nitrosamines and polycyclic aromatic hydrocarbons, which can induce DNA damage and promote tumor development 6

Ultimately, the best tool is the one that fits you the one that satisfies your specific cravings and provides a convincing substitute for the act of smoking

In this study, the IOC score was 0.84, indicating that the items had strong content validity and were aligned with the research objectives