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Researchers at the National Institute on Drug Abuse asked 10 adult smokers to smoke four different types of cigarettes: American Spirit: an unfiltered, additive-free cigarette Irie Bidi: an unfiltered, strawberry flavored bidi Sher Bidi: an unfiltered, non-flavored bidi Regular Brand: a filtered cigarette the subject usually smoked Levels of nicotine in the blood and exhaled carbon monoxide were measured in each of the 10 smokers before and after smoking each of the four types of cigarettes