Another study showed that compared to air-exposed controls, IQOS-exposed mice (14 days) had significantly decreased concentrations of reduced glutathione and increased percentage of oxidized glutathione in lung tissues, both markers of oxidative stress 44
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However, as of today, iQOS is only available in Nagoya. Melchior said the awareness rate of iQOS exceeds 42%, and that over 30% of adult smokers who have purchased an iQOS device are fully or predominantly using it instead of regular cigarettes
Federal Institute for Risk Assessment (BfR) While his assessments emphasize the need to protect non-smokers, and especially young people, from starting to smoke, he also acknowledges the potential for risk reduction for smokers