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LaVoie responded by saying, We gave them (the laboratory animals) less than one-third the dose of eugenol which is delivered to the lungs by one clove cigarette: less than one-third the amount of eugenol in one clove cigarette kills 50% of the animals. UC Irvines Phalen said intratracheal studies can be useful and important in looking at the toxicity of something the lung has been exposed to