Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry
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The most prominent result is the activation in left motor cortex which can plausibly be attributed to hand and oro-facial movements associated with the smoking task
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D Ornish, G Weidner, W R Fair, R Marlin, E B Pettengill, C J Raisin, S Dunn-Emke, L Crutchfield, F N Jacobs, R J Barnard, W J Aronson, P McCormac, D J McKnight, J D Fein, A M Dnistrian, J Weinstein, T H Ngo, N R Mendell, P R Carroll