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In these cases, the evidence relies on a combination of studies showing the dysregulatory effect of smoking and/or cigarette smoke constituents on the above factors and studies showing the pathogenetic effect of these factors on various non-communicative diseases

Second, the primary outcome variables in many cases relied on self-reported data, which incurs a higher risk of bias

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Their hard work, low income, and low literacy possibly cause them to be unaware of smoking harms and SHS-attributed health harms to non-smokers