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Additionally, the flavourings and sweeteners used in e-liquids can activate the brains reward centres, leading to cravings for sweet or fatty foods

The agency has struggled to stop e-cigarette makers who continue selling vapes despite the FDAs rejection of the products, as well as manufacturers who never bothered to apply for authorization, and counterfeiters hoping to earn as much money as possible before being shut down

Those who rely only on the dashboard often reach incorrect conclusions

"We believe the public health benefits and the potential to save millions of lives, both in the near and long term, support this effort," Gottlieb said

PMID 24309905