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The state heavily restricts flavored products, bans vaping in most public spaces, regulates online sales, and prohibits cannabis vaping in public or vehicles

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Conversely, reduced expression of the antioxidant transcription factor nuclear factor E2-related factor 2 (Nrf2) due to DNA hypermethylation in COPD, may increase the susceptibility of bronchial epithelial cells to oxidative stress-dependent cell death (181)

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Writers must balance subtlety with clear purpose to avoid heavy-handedness or confusion