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In this process the important role plays decrease of ex- pression of genes responsible for formation of collagen, elastin and fibronectin, which, in turn, accompanied by metabolic imbalance of fibroblasts, in particular metabolism of fibrillin in these cells [5-10]

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How do we create and then chisel away at those images of others, of loss, of suffering, of unspeakable helplessness so that they become works of art that aim for a shared humanity

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without it, the device will not work properly