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It has also been used for centuries as a natural expectorant (cleans the lungs), to reduce inflammation, muscle tension, and hyperactivity and to create repulsion against the flavour of tobacco

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However, PAHs and their metabolites, which are relatively strong the aryl hydrocarbon receptor (AhR) ligands, exert both anti-estrogenic and estrogenic effects subsequently inhibiting or enhancing estrogenic signaling via crosstalk between AhR and estrogen receptors (ERs) or interfere with the AhR-controlled enzymes [41, 44]

We think its mostly a peripheral problem (i.e